How it works
Lumoral is based on a dual-wavelength LED light which activates Lumorinse (exocellular) and bacteria porphyrins (endocellular), resulting in the formation of reactive oxygen species (ROS). ROS and heat induce a series of photochemical and biological events that cause irreversible inactivation leading to the death of undesired bacteria.
The Photosensitizer in Lumorinse mouth rinse is Indocyanine green (ICG). ICG is a color molecule, that has been granted FDA approval in 1959. Since, it has been used in several medical solutions - for example, in cardiac output or hepatic function monitoring. In these solutions it is administered intravenously.
Red Light Near-infrared light reacts with the green sensitizer: the reaction brakes the cell membrane of the bacteria. Our own immune cells that can surround and kill microorganisms use the same method to protect our body from harmful pathogens.
Antibacterial Blue Light Bacterial cells contain naturally occurring porphyrins and flavins. Blue light reacts with these molecules inside bacterial cells in a similar way. The bacterial cells are destroyed both inside and outside. They are unable to develop a resistance to the method. The combined use of Lumoral's photodynamic therapy and antibacterial blue light has been shown to be very effective against harmful oral bacteria, and no bacterial resistance is developed against their simultaneous use, even with repeated use.